One thing nice is Allspice is non toxic and if you read the article in full the researchers were kind of astonished themselves to see it work and target the androgen receptor. The University of Miami hopes not too far down the road to start clinical trials for men being treated for prostate cancer.
They are not far enough along yet but in one statement in the article is says they are also curious if this could help even “prevent” some cancer development.
This is kind of amazing with the finding as look at the millions and billions spent on developing prostate cancer drugs and this in no way is saying it would be a full on replacement, too early to tell. I can find some Allspice in kitchen with my other spices. Again the lack of toxicity here is a real plus for sure. The clinical trials they hope to begin would be for men who have not reached the point of needing treatment yet, so a safe place to start with just using it as a daily supplement.
Now for a little more good news, they have also shown that the extract also slows the speed of breast cancer too, a double win for both sexes but researchers are not as far along and there’s a different polyphenol. BD
“Androgen receptor, or AR for short, is the principal drug target for the treatment of prostate cancer, but there is no drug that completely eliminates AR. This complex compound in allspice seems to do that,” Lokeshwar said. “The most interesting data shows that it actually kills tumor cells which express the very specific prostate cancer marker, the androgen receptor. That is not to say that people should start eating allspice with every meal, but there exists the potential that the slow and steady consumption of this chemo-dietary agent may slow or even prevent prostate cancer.”
Essential to jerk seasoning, allspice is known for flavoring Jamaican and other cuisines around the world with a blend of cinnamon, cloves, nutmeg and pepper but, according to a new study by Miller School researchers, the aromatic spice could be known one day for impeding the growth of, or maybe even preventing, prostate cancer, the No. 2 cancer-killer of men in the U.S.
In the study published online May 8 in the Oxford Journals’ Carcinogenesis and led by Bal L. Lokeshwar, Ph.D., professor of urology and radiation oncology and Co-Director of Research in the Department of Urology, researchers demonstrated that Ericifolin, a complex compound in the allspice berry, significantly slows the growth of prostate cancer tumors by suppressing the androgen receptor (AR). A molecule central to the growth and metastasis of prostate cancer, AR enables prostate cancer cells to survive even after hormone therapy, which along with surgery and radiation is the standard treatment for prostate cancer.
They also hope to begin a clinical trial in the near future with UHealth patients who are under active surveillance for early-stage or slow-growing prostate cancer, which does not yet warrant treatment. Since allspice is not toxic, Lokeshwar reasons those patients would be ideal candidates to take Ericifolin as a daily dietary supplement.
They are not sure yet which one but, in Lokeshwar’s mind, that discovery raises the possibility that allspice may have many anticancer properties worth exploring.
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